Ph.D. Program in Structural and
Computational Biology and
Molecular Biophysics

David J States

David J States

The University of Texas Health Science Center at Houston

Department:
Address: The University of Texas School of Health Information Sciences at Houston
7000 Fannin, Room 830
Houston, Texas 77225

Phone: 734-615-5510
Fax: (713) 500-3907
Email: David.J.States@uth.tmc.edu
Web: www.stateslab.org/contact.html

Education

B.A. in Biochemistry Harvard University, 1975
M.D., Ph.D. in Biophysics Harvard University, 1983

Honors

Research Topic

Multidisciplinary computational applications for biomedicine.

Research Description

The States Group develops multidisciplinary computational applications for biomedicine. We have focused on high throughput experimental technologies and ways to enhance knowledge acquisition using novel algorithms and strategies for data acquistion. Early work invovled the development of pure absorption phase methods for multi-dimensional NMR spectroscopy, enhanced lane tracking and basecalling algorithms for genome sequencing and more recently improved algorithms for the analysis of proteomics and mass spectrometry.

The States Group is also engaged in molecular biology data integration. Projects have included physical map assembly, genome annotation, the analysis of gene expression profiles, databases for molecular interactions and automated natural language processing.

Current projects in the group include:

Proteomics and mass spectrometry
Cellular proteomics technology
Proteomics of the mononuclear phagocytes and tumor associated macrophages
Alternative splicing in cancer

Molecular biology data integration
Molecular interactions mapping and data integration
Systems biology of mononuclear phagocytes and the macrophage
Information retrieval and natural language processing

Selected Publications

Lab Members

Lab Photos

Last edited on: October 23, 2009