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David Gorenstein
The University of Texas - Houston Medical SchoolDepartment:Address: 1825 Pressler Street Houston, TX 77030 Phone: (713) 500-2233 Fax: Email: david.g.gorenstein@uth.tmc.edu Web: www.hbcg.utmb.edu/faculty/gorenstein/ |
Education
M.I.T. Cambridge, Mass. S.B. 1963-1966 Chemistry
Harvard Cambridge, Mass. A.M. 1966-1967 Chemistry
Harvard Cambridge, Mass. Ph.D. 1966-1969 Chemistry
Honors
American Association for the Advancement of Sciences, elected Fellow, 1994.
Guggenheim Fellowship, 1986.
Fulbright Senior Research Fellowship, 1977-1978.
Fulbright International Lectureship Award, 1978.
Alfred P. Sloan Fellowship, 1975-1979.
Texas Higher Education Coordinating Board, Award for Research Excellence in Creation of the Gulf Coast Consortia (awarded to D. Gorenstein/UTMB on behalf of the 6 Houston/Galveston member institutions of the GCC), 2005
Who's Who in America, Who’s Who in the World, Who’s Who in American Education (among others)
Editor, Bulletin of Magnetic Resonance, 1982-2000.
Editor, NMR in Biophysics, WEB on-line 'textbook' sponsored by the Biophysical Society, 1996-2000.
Editorial Board, The Open Magnetic Resonance Journal, 2007-
Editorial Board, Journal of Magnetic Resonance, 1992-1999.
Editorial Board, Biophysical Journal, 1992-1998.
Editorial Board, Magnetic Resonance Reviews, 1983-1993.
Research Topic
Mol. Medicine Cardiovascular Research
Research Description
Research Description I currently have a major program in proteomics and nanomedicine for both diagnostics and therapeutics in both infectious diseases and cancer.
Selected Publications
- Structural and Functional Elements of the Promoter Encoded by 5'UTR of Venezuelan Equine Encephalitis Virus Genome. R. Shylini, S. Atasheva, V. Thiviyanathan, D. G. Gorenstein and I. Frolov J. Virology In press (2009).
- The 5'UTR-specific mutation in VEEV TC-83 genome has a strong effect on RNA replication and subgenomic RNA synthesis, but not on translation of the endoced proteins. R. Shylini, V. Thiviyanathan, D. G. Gorenstein and I. Frolov Virology 387:211-221, 2009.
- Analysis of the Differential Host Cell Nuclear Proteome Induced by Attenuated and Virulent Homorrhagic Arenavirus Infection. G.C. Bowick, H.M. Spratt, A.E. Hogg, J.J. Endsley, J.E. Wiktorowicz, A. Kuroshy, B.A. Luxon, D.G. Gorenstein and N.K Herzog J. Virol. 83:687-700, 2009.
- NMR Assignments of the Sylvatic Dengue 1 Virus Envelope Protein Domain III. D. E. Volk, K. M. Anderson, S. H. A. Gandham, F. J. May, L. Li, David W. C. Beasley, A. D. T. Barrett and D. G. Gorenstein Biomol. NMR Assigments 2:155-157, 2008.
- Base-pairing Properties of the Oxidized Cytosine Derivative, 5-Hydroxy Uracil. V. Thiviyanathan, A. Somasunderam, D. E. Volk, T.K. Hazra, S. Mitra and D. G. Gorenstein Biochem. Biophys. Res. Commun. 366:752-757, 2008.
- Combinatorial selection of a single stranded DNA thioaptamer targeting TGF-beta-1 protein. J. Kang, M. S. Lee, J. A. Copland, B. A. Luxon and D. G. Gorenstein Bioorg. Med. Chem. Lett. 18(6):1835-1839, 2008.
- Bead-based Approaches to Develop Thioaptamers for Diagnostics and Therapeutics. X. Yang, D. Beasley, J. Engelhardt, M. Shumbera, B. A. Luxon and D. G. Gorenstein Phosphorus, Sulfur, and Silicon and the Related Elements 183(2):469-472, 2008
- Ab initio base-pairing energies of an oxidized thymine product, 5-formyluracil, with standard DNA bases at the BSSE-free DFT and MP2 theory levels. D. E. Volk, V. Thiviyanathan, A. Somasunderam and D. G. Gorenstein, Org. Biomol. Chem. 2007, 5(10), 1554-1558.
- NMR Assignments of the Yellow Fever Virus Envelope Protein Domain III D. E. Volk, S. A. Gandham, F. J. May, A. Anderson, A. D. T. Barrett and D. G. Gorenstein. Biomolecular NMR Assignments 2007, 1(1):49-50, 2007.
- Solution Structure of the Envelope Protein Domain III of Dengue-4 Virus D. E. Volk, Y.-C. Lee, X. Li, V. Thiviyanathan, G. D. Gromowski, L. Li, A. Lamb, D. W. Beasley, A. D. T. Barrett and D. G. Gorenstein, Virology 2007, 364(1), 147-154. (PMCID: PMC1950219)
- Magnesium ion is an effective inhibitor of Escherichia coli to heparin. J. Kang, M. S. Lee & D. G. Gorenstein, J. Microbiol. Methods 71(3):340-342, 2007.
- Combinatorial Selection of a RNA Thioaptamer that binds to Venezuelan Equine Encephalitis Virus Capsid Protein. J. Kang, M. S. Lee, S. J. Watowich and D. G. Gorenstein FEBS Lett. 581(13):2497-2502, 2007.
Lab Members
Current Graduate Students
Current Post Docs
Lab Photos
Last edited on: September 22, 2009