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Zhongmin WangDepartment: Principal Scientist Address: New Century Pharmaceuticals, Inc. 895 Martin Rd., Huntsville, AL 35824 Phone: 256-461-0024 ext 229 Fax: 256-461-4224 Email: zwang@newcenturypharm.com Web: |
Education
B. S. Physics, University of Science and Technology of China (1991)
Ph. D., Structural and Computational Biology and Molecular Biophysics (1998)
Post Doc, Baylor (1999)
Honors
Research Topic
X-ray Structure and Function of Two Proteins: A Phosphate Transport Receptor and Adenosine Deaminase
Research Description
Selected Publications
- Ledvina PS, Tsai AL, Wang Z, Koehl E, Quiocho FA. Dominant role of local dipolar interactions in phosphate binding to a receptor cleft with an electronegative charge surface: equilibrium, kinetic, and crystallographic studies. Protein Sci. 1998 Dec;7(12):2550-9.
- Wang Z, Quiocho FA. Complexes of adenosine deaminase with two potent inhibitors: X-ray structures in four independent molecules at pH of maximum activity. Biochemistry. 1998 Jun 9;37(23):8314-24.
- Wang Z, Luecke H, Yao N, Quiocho FA. A low energy short hydrogen bond in very high resolution structures of protein receptor--phosphate complexes. Nat Struct Biol. 1997 Jul;4(7):519-22.
- Wang Z, Choudhary A, Ledvina PS, Quiocho FA. Fine tuning the specificity of the periplasmic phosphate transport receptor. Site-directed mutagenesis, ligand binding, and crystallographic studies. J Biol Chem. 1994 Oct 7;269(40):25091-4.
- Wardell M, Wang Z, Ho JX, Robert J, Ruker F, Ruble J, Carter DC. The atomic structure of human methemalbumin at 1.9 A. Biochem Biophys Res Commun. 2002 Mar 8;291(4):813-9.
Last edited on: June 08, 2005