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Yifei Kong, Ph.D. Baylor College of Medicine Department: Postdoc, Dept. of Chemistry and Chemical Biology, Harvard University Address: 12 Oxford St. Cambridge, MA 02138 Phone: 617-495-8997 Fax: 617-496-4793 Email: yifeik@tammy.harvard.edu Web:

Education

B.S. Biochemistry, Nanjing University (1997)
Ph.D., Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine (2005)
Postdoctoral Fellow, in the lab of Dr. Martin Karplus, Harvard University

Honors

Research Topic

Multiscale Simulation and Modeling

Research Description

Molecular dynamics simulation

Selected Publications

• Yifei Kong and Jianpeng Ma (2001). Dynamic Mechanisms of the Membrane Water Channel Aquaporin-1 (AQP-1). Proc. Natl. Acad. Sci. USA. 98: 14345-14349.
• Yufeng Shen, Yifei Kong and Jianpeng Ma (2002). Intrinsic Flexibility and Gating Mechanism of the Potassium Channel KcsA. Proc. Natl. Acad. Sci. USA. 99: 1949-1953.
• William H. Noon, Yifei Kong and Jianpeng Ma (2002). Molecular Dynamics Analysis of A Buckyball-antibody Complex. Proc. Natl. Acad. Sci. USA. 99: 6466-6470.
• Yifei Kong, Yufeng Shen, Tiffany E. Warth and Jianpeng Ma (2002). Conformational Pathways in the Gating of E.coli Mechanosensitive Channel. Proc. Natl. Acad. Sci. USA. 99: 5999-6004.
• Dengming Ming*, Yifei Kong*, Salih J. Wakil, Jacob Brink, and Jianpeng Ma. (2002). Domain movements in human fatty acid synthase by quantized elastic deformational model. Proc. Natl. Acad. Sci. USA. 99: 7895-7899 (*equal contributions)
• Dengming Ming, Yifei Kong, Maxime A. Lambert, Zhong Huang, and Jianpeng Ma. (2002). How to describe protein motion without amino acid sequence and atomic coordinates. Proc. Natl. Acad. Sci. USA. 99: 8620-8625
• Dengming Ming, Yifei Kong, Yinghao Wu, and Jianpeng Ma. (2003). Substructure synthesis method for simulating large molecular complexes. Proc. Natl. Acad. Sci. USA. 100:104-109.
• Yifei Kong, Dengming Ming, Yinghao Wu, James K. Stoops, Z. Hong Zhou, Jianpeng Ma. (2003). Conformational flexibility of pyruvate dehydrogenase complexes: a computational analysis by quantized elastic deformational model. J. Mol. Biol. Jun 27;330(1): 129-135.
• Dengming Ming, Yifei Kong, Yinghao Wu, Jianpeng Ma. (2003). Simulation of F-actin filaments of several microns. Biophys. J. Jul;85(1):27-35.
• Yifei Kong & Jianpeng Ma (2003). A structural-informatics approach for mining beta-sheets: locating sheets in intermediate-resolution density maps. J. Mol. Biol. Sep.12 332(2): 299-413.
• Terence C. Flynn, Liskin Swint-Kruse, Yifei Kong, Christopher Booth, Kathleen S. Matthews and Jianpeng Ma. (2003). Allosteric Transition Pathways in the Lactose Repressor Protein Core Domains: Asymmetric Motions in a Symmetric Homodimer. Protein Science 12: 2523-2541.
• Brink J, Ludtke SJ, Kong Y, Wakil SJ, Ma J, Chiu W. (2004). Experimental verification of conformational variation of human fatty acid synthase as predicted by normal mode analysis. Structure (Camb). Feb;12(2):185- 191.

Last edited on: June 28, 2005